![macvector recombination macvector recombination](https://wwwnc.cdc.gov/eid/images/13-0999-F2-tn.jpg)
As this early example demonstrated, any practical application of synthetic biology will naturally evolve into and require synthetic genomics.Īlso, as genomics evolved from early sequencing efforts, it shifted away from organisms that could easily be grown in pure culture. coli genome to increase the yield to economically beneficial levels.
![macvector recombination macvector recombination](http://macvector.com/blog/wp-content/uploads/2009/11/PCRFragmentInserted1.jpg)
The pathway for the production of this molecule from glycerol is coded for by only a few genes however, Dupont also had to make dozens of changes in the E. A telling example of this is the Dupont Escherichia coli strain that has been engineered to produce 1,3 propanediol. However, that pathway must function in a biochemical and regulatory context with many inputs and outputs. Most synthetic biology efforts might only have the scope of engineering an individual biosynthetic pathway. Synthetic genomics is defined and distinct from genetic engineering as the engineering and manipulation of the genetic material of an organism on the scale of the whole genome either in terms of number of base-pairs, or number of loci engineered.